Initiating a meaningful convo online

So you see an attractive guy in people you might know with quite a few mutual friends, or they send you a request themselves. What do you do?I recently got a load of friend requests from guys on facebook, many of them are not only attractive, but from their updates we have similar interests, and some seem to have a great personality.Whats the best way to make an impact or have a meaningful convo with someone youve never met in person?